Difference between revisions of "CellDesigner/C3/Customizing-Diagram-Layout/English-timed"

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Revision as of 12:18, 2 November 2017

Time Narration
00:01 Hello everyone.Welcome to this tutorial on ‘Customizing Diagram Layout’.
00:08 In this tutorial, we will learn how to: Change color, shape and width of a Reaction line
00:19 Add Anchor points to a Reaction lineAlign Components Show/hide Reaction ids
00:30 We will also learn how to: Add notes to ComponentsEdit ProteinEdit information
00:39 And get a bird’s eye view of the diagram
00:44 To record this tutorial, I am usingUbuntu Linux OS 14.04 CellDesigner version 4.3 Java version 1.7
01:01 To follow this tutorial, learners should be familiar with:Undergraduate Biochemistry and

CellDesigner interface.

01:12 If not, for relevant CellDesigner tutorials, please visit the Spoken Tutorial website.
01:20 Let us begin.
01:22 The assignment for one of the previous tutorials was- To build a process diagram for Methionine Biosynthesis.
01:32 I am going to use that same diagram as the example for this tutorial.And I will demonstrate how to customize it.
01:43 Let me switch to CellDesigner interface.
01:47 What you see here is the process diagram for Methionine Biosynthesis.
01:53 Pause the tutorial here and open the Methionine Biosynthesis process diagram that you created.
02:01 If you do not have a saved file, you may open from the code file provided.
02:08 Now, let me start customizing the diagram.
02:12 Let us go back to the Cell designer interface
02:16 To start with, I will change the width and color of a Reaction line.
02:22 To do so, I am selecting the State Transition between Homoserine and Succinyl homoserine.
02:30 Now, go to “Component” in the main menu bar.
02:35 And click on “Change color & shape” option.
02:39 Alternately, you may right-click on a Reaction line and select “Change color & shape” option.
02:47 A dialog box named “Change color & shape” appears on the screen.
02:53 For a thicker Reaction line, change the Line Width from 1.0 to a higher value.
03:02 I will change this to 3.0
03:06 To change the color of the Reaction line, go to the Color panel.
03:12 In the Color panel we can see a color wheel, with a pointer like handle.
03:19 Click and hold the pointer and rotate to select the preferred color.
03:25 I will select a shade of blue.
03:28 Next, click anywhere inside the color triangle.
03:34 Now, Click and drop the small circle at the pointer.
03:40 After all the modifications are done, click on Apply and then on Ok.
03:48 Observe that the Reaction line is now thicker and in shade of blue.
03:55 Next we will learn how to add Anchor points on the Reaction line.
04:01 And why Anchor points are useful to- Turn around the Reaction lines
04:09 Give them a proper shape And place them in the correct position on the draw area.
04:16 Lets come back to the CellDesigner interface.
04:20 Select any Reaction line.
04:23 I will select the same State Transition reaction line between- Homoserine and Succinyl Homoserine.
04:31 On this line, using the cursor, choose the exact position where the Anchor point has to be placed.
04:39 Upon selection of the exact point, right-click and select Add Anchor Point.
04:47 You will see the newly added Anchor point at the exact chosen position on the Reaction line.
04:55 Let me show you how Anchor Points can help to modify a Reaction line.
05:03 Let me open a new window and name it Anchor. Click OK
05:11 Now click on the icon for GTP/GDP
05:18 And click anywhere on the draw area.
05:22 Right-click on Reaction line and click on Add Anchor point
05:29 Drag and drop the Reaction line anywhere on the draw area.
05:37 Next we will see how to align the components on the draw area.
05:44 Let us come back to the Methionine biosynthesis process diagram window
05:50 Click anywhere on the draw area to uncheck the highlighted Reaction line.
05:56 Now, hold the 'Shift' key and click on multiple Species on the draw area.
06:04 Go to Edit menu, scroll down select Alignment and click on the Alignment type.
06:15 Alternately, click on the icon for Alignment on the toolbar.
06:21 Explore other Alignment options on the toolbar on your own.
06:27 Let us undo the alignment and move ahead.
06:31 While working on a Reaction, how can we show/hide Reaction ids on a process diagram?
06:39 Let’s learn that.
06:41 Go to 'View', scroll down and uncheck the 'Show Reaction Id'.
06:48 The Reaction ids on the respective reactions on the draw area will not be visible any more.
06:55 In case, you wish to show the Reaction Id do the following.
07:01 Go to 'View', scroll down and click on the 'Show Reaction Id'.
07:08 The Reaction ids will appear on the respective reactions on the draw area.
07:15 We can also add notes to all the Components (Compartment, Species or Reaction) on the draw area.
07:21 Let us learn how to do that.
07:24 Right-click on a Species on the draw area.
07:28 I will click on CoA.
07:32 Scroll down and click on the ‘Species Notes’.
07:35 A pop up menu is displayed
07:38 A dialog box 'Species Notes' pops up. Type the text related to the Species
07:46 I will type the following.
07:49 Click 'OK'.
07:51 Observe that the notes information is displayed in the Notes Area.
07:58 Alternately, to add notes to a Species, click on a Species on the draw area.
08:06 I will click on Succinate.
08:09 Then, click on Edit Notes tab, located at the bottom right corner of the CellDesigner window.
08:18 A pop up window will appear.
08:21 Type the text related to the Species-
08:25 I will type and click 'OK'.
08:30 In the same manner we can edit a Protein.
08:35 To do so, right-click on a component on the draw area.
08:40 I will click on Homoserine succinyl transferase.
08:46 Scroll down and click on Edit Protein.
08:51 A dialog box named Protein appears on the screen.
08:55 Enter the name of the Protein in the name box.
09:00 I will type O-succinyltransferase in the name box.
09:06 Click on ‘Update’ and close the dialog box.
09:11 We can also add regions to a Protein.
09:15 Right-click on a Protein on the draw area.
09:19 I will right click on O-succinyltransferase.
09:24 Scroll down and click on Edit Protein.
09:29 A dialog box, Protein, appears on the screen.
09:33 Under the tab ‘residues/regions’, click on the 'Add' button.
09:40 In the dialog box - ModificationResidue/Bindingregion:
09:46 Select the ‘Type’ from the drop down menu as ‘Binding region.
09:52 Change the size and angle by moving the cursor at the required value.
09:59 For this demo, I will select- Size as 15 andAngle 38
10:09 Then click on ‘Close’.
10:12 Click on the Update
10:14 And close the box.
10:17 As we do not require to add region in the Methionine Biosynthesis, I will undo these changes.
10:25 Next, let us learn to edit information.
10:30 Right-click on the component on the draw area.
10:33 I will click on Homoserine.
10:37 Scroll down and click on ‘Edit Information’.
10:41 A dialog box ‘Edit Information’ appears on screen
10:46 In the dialog box do the following- Under the tab ‘state’ select Open.
10:54 Under the tab ‘prefix’ select mt.
10:59 Under the tab ‘label’ select dna.
11:04 Click on ‘Ok’.
11:07 You can see the information mt:dna displayed on the draw area
11:15 I will undo Edit Information, as we do not require it in Methionine Biosynthesis.
11:23 In some cases, the process diagram can be a complicated one.
11:28 In such cases, Bird's eye view can help as it is convenient to navigate inside a big model.
11:37 Click the Bird's eye view icon.
11:41 Drag the red square in the Bird’s Eye View.
11:46 Observe that the view on the draw area moves accordingly.
11:52 This brings us to the end of this tutorial.
11:56 Let us summarize. In this tutorial, we have learnt how to: Change- color, shape and width of a Reaction line
12:07 Add Anchor points to a Reaction line Align Components And show/hide Reaction id’s
12:18 We have also learnt how to- Add notes to Components
12:23 Edit Protein/Gene Edit Information
12:27 And get the Bird’s Eye View of the diagram
12:32 For Assignment Create a Glycolysis Process Diagram using tools in CellDesigner.
12:41 Explore different shapes of Reaction line
12:47 Watch the video at the following link It summarizes the Spoken Tutorial project.
12:52 If you do not have a good bandwidth please download and watch it.
12:57 The Spoken Tutorial Project Team - Conducts Workshops And gives certificates for those who pass an online test.
13:06 For more details, please write to contact@spoken-tutorial.org
13:13 Spoken Tutorial Project is a part of Talk to a Teacher project. It is funded by NMEICT, MHRD, Government of India. More information on this Mission is available at the given link.
13:29 This is Bella Tony from IIT Bombay signing off.

Thank you for joining.

Contributors and Content Editors

Jyotisolanki, Sandhya.np14